products / Oxymetholon

Composition:

50 mg Oxymetholone per tablet.

Indications:

Protein synthesis disorders, cachexia diverse genesis, trauma, extensive burns after irradiation infectious diseases, muscular dystrophy, osteoporosis, negative nitrogen balance corticosteroid therapy, aplastic anemia and hypo.

Contra- indications:

Hypersensitivity to the drug, prostate cancer, breast cancer in men, breast carcinoma in women with hypercalcemia, CPI, severe atherosclerosis, nephritis, nephrotic syndrome, hepatic and renal function, acute and chronic prostatitis, pregnancy, lactation.

Administration:

The recommended daily dose for adults and children is 1-5 mg / kg / day. The usual effective dose of 1-2 mg / kg / day, but may require higher doses, so it is necessary to individual doses. The answer does not come immediately, so the treatment is 3-6 months minimum. Patients with congenital aplastic anemia require continuous treatment with the maintenance dose.

Medical action:

Oxymetholone is an anabolic steroid. Reaching into the cell nucleus, stimulates the genetic apparatus of the cell, leading to increased synthesis of DNA, RNA and structural proteins, activates enzymes of respiration chain tissue and enhancing respiration tissue, oxidative phosphorylation, ATP synthesis and intracellular aggregation macroergic. Stimulates anabolic and inhibits catabolic processes those caused by glucocorticoids. Leads to increased muscle mass, reduce fat deposits, improves trophic tissues, promotes calcium deposits in the bones, and retains of sodium and water in the body. The action is the enhancement of hematopoietic erythropoietin synthesis. Androgenic (moderate) may contribute to the development of secondary sexual characteristics of male type.

Precautions:

At the first signs of virilization of patients (deepening of the voice, hirsutism, acne, clitoromegaly) administration should be stopped to avoid irreversible changes. It may occur suppression of plasma coagulation factors II, VII, VII and X, and prothrombin time increased. A systematic control of the lipidemia and cholesterol is necessary. Pediatric use should be made by an experienced specialist to avoid premature epiphyseal bone calcification.

Side effects:

Women - virilization symptoms, inhibition of ovarian function, menstrual disorders, hypercalcemia.

Men: In the prepubertal period - virilization symptoms, skin hyperpigmentation idiopathic withholding or stopping the growth (calcification of epiphyseal growth zones tubular bones) during postpubertary - bladder irritation, gynecomastia, priapism, and the elderly period - hypertrophy and / or carcinoma prostate.

In men and women - the progression of atherosclerosis, peripheral edema, impaired liver function with jaundice, changes in blood count, pain in bones sockets, hypo coagulation and prone to bleeding.

Over dosage:

If overdose is suspected, contact your Doctor immediately.